Adapalene, which is the gentlest in the retinoid family, also has some ability to improve the appearance of sun damage, said board-certified dermatologist Dr. Macrene Alexiades, who is also based in New York.

“Generally speaking, over-the-counter retinol products are suitable for those with mild issues… [T]hose who need a stronger over-the-counter version… would use adapalene or Differin,” a name-brand adapalene product, Alexiades said.

Both Alexiades and Ostad said that, like all retinoids, adapalene has the potential to be drying, so it’s best to use just a pea-sized amount on the whole face, only at night, and to pair it with a moisturizer.

Most adapalene products — the best-known of which is Differin — have the same .1% concentration of the ingredient. Ahead, you can shop all of the options we found on Amazon and read some reviewer comments about their effectiveness.

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